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List:       spamassassin-users
Subject:    Re: Possibly some good news - OT
From:       David Niklas <doark () mail ! com>
Date:       2016-10-21 19:54:13
Message-ID: 20161021155413.5582300b () ulgy_thing
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On Tue, 11 Oct 2016 10:49:36 -0700
Marc Perkel <support@junkemailfilter.com> wrote:

> Hi everyone,
> 
> Well, maybe there's some good news. Traditional solutions for stage 4
> lung cancer are not good but on the cutting edge of technology it looks
> much better. Below is a letter I sent to a former employer explaining
> my current status. The bottom line is that I think I have figured out
> the best science based treatment that has ever been tried for my
> specific kind of lung cancer and that means, if I'm right, that I have
> more time that I thought.
> 
> Also - you can follow me on Twitter @mperkel
> 
> 
> Hi Cindy,
> 
> Please share this with EFF Staff and others. First I'd like to thank
> you for including me in the EFF staff group photo. That was very
> meaningful to me. It was great spending time with everyone at the
> Pioneer Awards.
> 
> So, the good news - it looks like there's a good chance I'm going to be
> around longer that I originally thought. Compressing a long story with
> a lot of adventure, traditional cancer therapies offered me very
> little. So I went to MD Anderson in Texas which is considered to be the
> nations most advanced research hospital. While I was traveling there
> some of Kaiser's tests came in that showed I had a very rare genetic
> profile in the cancer called RET fusion mutation. And it so happens
> that MDA had a phase 1 trial of a drug combination that had only been
> tried on 9 people on the planet so far but had 100% response. (response
> is tumor shrinkage).
> 
> Although this was what looked like the ideal treatment - just 2 pills -
> no chemo - actually getting the treatment was challenging and a long
> story that was a hard fought battle. But in the end I got Kaiser to
> prescribe these same 2 drugs, not as part of a study, and because of
> that I don't have to travel monthly to Texas to get this treatment nor
> endure drug escalation experiments of the phase 1 trial. And I can mix
> in a few other ideas in the plan without messing up anyone's data. So I
> got what I want and I got it on my terms. One thing that I did find out
> is a darker side of the cancer industry where MDA's interests were
> focused mostly on the billing issues and were willing to hold my life
> hostage to get money. But that was the aspect that I leveraged to get
> the treatment and on my own terms.
> 
> The treatment consists of 2 pills, Vandetanib in Combination with
> Everolimus. Vandetanib (Caprelsa) is a thyroid cancer drug that targets
> the same RET fusion I have in my lung cancer, and is much more common
> in thyroid cancer. Everolimus (Afinitor) is a more interesting drug.
> it's in a class called mTor inhibitors which is the same kind of drugs
> being researched for cellular epigenetic regeneration to reverse old
> age at the cellular level.
> 
> I share a theory with some others on the cutting age of both the cancer
> and anti-aging community that the biggest risk factor for cancer is old
> age. And the cure for cancer will be in most part the cure for aging
> and cancer, along with diabetes, Alzheimer, and other age related
> diseases will be cured at the same time. So the idea that one of the
> magic drugs happened to be an anti-aging drug was in line with this
> theory. Although Afinitor has too many side effects to be used as a
> nutritional supplement, because I'm lucky enough to have cancer I get
> drugs that other people don't have access to.
> 
> While I was waiting for access to this treatment (it took 3 weeks) I
> started doing my own research to put together my own drug cocktail in
> the mean time. Because of all the rules and regulations in the medical
> world they have to move far more slowly than optimal. But there are a
> lot of papers online as to the kinds of things they are looking at
> trying next. And because of the way I think outside the box and my lack
> of limitations, the likelihood that I could create a superior outcome
> compared to short term certain death is rather high. And in comparison
> to what traditional therapies offer there is really no additional risk.
> 
> One thing that I noticed was that all the experimental substances in
> the anti-aging world were also the cutting edge experimental substances
> in the cancer world. The leading mind in the anti-aging world is a guy
> named Dr. David Sinclair, who became famous for discovering the
> Resveritrol molecule in red wine. Since then he has come up with
> several more powerful substances and no Glaxo Smith Kline has got 3/4
> of a billion dollars invested in his work and some of his latest stuff
> is in human trials now. He expects to be able to kick the age limit up
> for 80 to 120 years.
> 
> Some of his intermediate work since Resveritrol is now available on
> Amazon without a prescription. One combination of 2 substances he's
> working on is Pterostilbene and Nicotinamide Riboside. One is a
> metabolic enhancer and the other is an mTor inhibitor, like Afinitor,
> that trigger the Surtuin enzymes that are responsible for epigenitic
> regeneration. Quite frankly, anyone over 45 years old should be taking
> these two drugs for their age reversing and disease prevention effects.
> And these 2 substances are all over the place in NIH studies for new
> cancer treatments for a variety of age related cancers.
> 
> After starting to take the Amazon drugs I did notice that I'm coughing
> up less stuff and when I started talking the prescribed drugs there
> seemed to be another reduction in mucus production. And that might be a
> good sign. So I am now talking all 4 drugs in combination, and if I'm
> right this is the most effective treatment for my specific lung cancer
> ever used. And it made enough sense to talk my oncologist into giving
> it a try.
> 
> At this point I'm optimistic that I have kicked the can down the road
> and that it's now years and not months. If I get 2 years out of this
> I'm calling it a win. And - I might be dead wrong, it might not work,
> and unexpectedly dropping dead is a side effect of Vandetanib. But even
> if that happened - this is still my best choice. In my battle against
> cancer, round one goes to me.
> 
> Ultimately in a battle which includes certain death the only variable
> is the quality of the battle. I'm beginning to relate to Klingons in
> Star Trek in that the fight is as important as the outcome. And this is
> the kind of fight that represents who I am and how my final adventure
> plays out. And in some ways defeating the hospital an insurance
> bureaucracy is probably tougher that figuring out how to cure cancer.
> So the idea of me beating this is very unlikely, but as Elon Musk would
> say, "Success is at least one of the possible outcomes."
> 
> Now I'm off to learn more of the big medical words to prepare for round
> 2. How hard can it be?
> 
> So - just wanted to share my possible good news and hopefully I will be
> around to be at 2 more Pioneer Awards in the future. That's my new
> working estimate.
> 
> Marc Perkel
> /root
> 

Ugh, he's going to live :) There is no one on this list who spams it
more then him :) Now we have to hear more about his miracle anti-spam
filter :)
No, seriously, congratulations and be careful, my mother is a doctor and
she reads all the time articles about many miracle drugs that don't do
what they are supposed to and some that kill (part), of you.
The USE Gov. is not just incompetent in one or two offices/branches.

Sincerely,
David
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