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List: bioconductor
Subject: [BioC] package for iAUC determination using gene expression data?
From: "Hooiveld, Guido" <guido.hooiveld () wur ! nl>
Date: 2014-04-28 19:14:51
Message-ID: EB992C246EB7BF449BC1E6B12AF7F6501F6270F5 () SCOMP0933 ! wurnet ! nl
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Hello,
I am analyzing an array dataset that is comprised of sequential measurements (m=10) \
after treatment with 2 experimental and 1 control compounds in multiple subjects \
(n=4). Among others I would like to determine the incremental area under the curve \
(iAUC) for each gene, its maximum and corresponding sample, as well as whether these \
are significant between any treatment. I was wondering whether anyone knows of a \
package that allows to do this relatively easy for omics (microarray) data.
Thanks very much for any pointer!
Guido
---------------------------------------------------------
Guido Hooiveld, PhD
Nutrition, Metabolism & Genomics Group
Division of Human Nutrition
Wageningen University
Biotechnion, Bomenweg 2
NL-6703 HD Wageningen
the Netherlands
tel: (+)31 317 485788
fax: (+)31 317 483342
email: guido.hooiveld@wur.nl
internet: http://nutrigene.4t.com
http://scholar.google.com/citations?user=qFHaMnoAAAAJ
http://www.researcherid.com/rid/F-4912-2010
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