[prev in list] [next in list] [prev in thread] [next in thread] 

List:       bioconductor
Subject:    [BioC] DEseq and FDR correction
From:       Oren Schaedel <orenis1 () gmail ! com>
Date:       2012-06-28 17:41:14
Message-ID: CADda6LifjbYKfM3XVhwz8yS5ff2dao2y44BM_6G6+vPUi66WOA () mail ! gmail ! com
[Download RAW message or body]

Hello everyone,
I'm new to the bioconducter list, and I have a question about DEseq:
Is it necessary to perform the FDR correction even though the variance is
estimated by the hierarchical model? I ask this because the values of
neighboring genes (hypothesis for the FDR) are used for the variance
estimation. Do we need to take into account these values again?


Thanks for your help

-- 
Oren Schaedel
Postdoctoral Fellow, Sternberg Lab.
California Institute of Technology
1200 E. California Blvd
Pasadena 91125
MC-156-29
USA

++1-626-395-8391

	[[alternative HTML version deleted]]

_______________________________________________
Bioconductor mailing list
Bioconductor@r-project.org
https://stat.ethz.ch/mailman/listinfo/bioconductor
Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor
[prev in list] [next in list] [prev in thread] [next in thread]